Rhapsody of the Seas: 11-Night Best Of Italy & Greece

Barcelona cruise port is the busiest in the Mediterranean, handling millions of passengers a year across multiple terminals. The city behind it earns that traffic.

La Spezia is a working Italian naval and commercial city on the Ligurian coast, but cruise passengers know it primarily as the gateway to Cinque Terre, the five colorful fishing villages clinging to the cliffs along a rugged stretch of coastline just north of the city. The La Spezia cruise port sits at the edge of the city center, a short walk from the train station that connects directly to the Cinque Terre villages.

Rome's cruise port is in Civitavecchia, a working port town about 80 kilometers northwest of the city. That distance is the single most important thing to understand about this stop.

Salerno is the eastern gateway to the Amalfi Coast, one of Italy's most celebrated stretches of coastline. Cruise ships dock at the Stazione Marittima in Salerno's port, a short walk from the city center and the starting point for trips along the legendary coastal road to Amalfi, Positano, and Ravello.

Messina cruise port sits at the northeastern tip of Sicily, directly across the narrow Strait of Messina from mainland Italy. Ships dock right at the city waterfront, making it one of the easiest Mediterranean ports to step off and explore.

Mykonos cruise port is one of the most instantly recognizable stops in the Greek islands. Whitewashed cube buildings cascade down hills to the Aegean Sea, blue-domed churches punctuate the skyline, and windmills stand sentinel on the ridge above Mykonos Town (Chora).

Kusadasi cruise port is Turkey's busiest and the primary gateway to Ephesus, one of the most significant ancient Greek and Roman cities in the world. The port sits on Turkey's central Aegean coast, about 95 kilometers south of Izmir, with ships docking at the Ege Ports cruise terminal right in the middle of town.

Rhodes is the largest of Greece's Dodecanese islands, sitting in the far southeastern Aegean Sea just 18 kilometers from the Turkish coast. The Rhodes cruise port is in the city of Rhodes on the island's northern tip, where ships dock right next to one of the best-preserved medieval old towns in Europe.

Santorini cruise port is one of the most visually striking arrivals in cruising. Ships anchor in the flooded caldera of a volcanic crater, with the whitewashed villages of Fira and Oia perched dramatically 1,000 feet above on the cliff edge.