16 Night Panama Canal Cruise

Nieuw Amsterdam

This 16-night Panama Canal cruise aboard the Nieuw Amsterdam by Holland America Line sails from San Diego to Fort Lauderdale (Port Everglades), departing October 2, 2026, calling at Puerto Vallarta, Huatulco, Puerto Chiapas, and 5 more ports, and returns October 18, 2026. Cabin prices start from $2,309 per person.

Days
16 nights
Departs
Oct 2, 2026
Ports
10
Returns
Oct 18, 2026
Sea days
7
Distance
3,935nm
Itinerary
Embark Port Sea
Day 1
Oct 2
Embark
San Diego, California
dep 16:00

San Diego is a major cruise port on the Southern California coast, about 120 miles south of Los Angeles and directly on the Mexican border. The B Street Cruise Ship Terminal and adjacent Broadway Pier sit in downtown San Diego along the Embarcadero waterfront, within walking distance of the Gaslamp Quarter, Seaport Village, and the USS Midway Museum.

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Day 2
Oct 3
At Sea
Day 3
Oct 4
At Sea
Day 4
Oct 5
Puerto Vallarta, Mexico
arr 08:00 · dep 17:00

Stretched along Banderas Bay with the Sierra Madre mountains rising directly behind the shoreline, Puerto Vallarta draws about 290,000 residents year-round and far more during the winter cruise season. The city has managed to grow as a tourist destination while keeping its Mexican identity intact, particularly in the Zona Romantica and the malecon (boardwalk) areas where local life and tourism coexist on the same streets.

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Day 5
Oct 6
At Sea
Day 6
Oct 7
Huatulco, Mexico
arr 10:00 · dep 17:00
Day 7
Oct 8
Puerto Chiapas, Mexico
arr 08:00 · dep 17:00
Day 8
Oct 9
Puerto Quetzal, Guatemala
arr 06:00 · dep 20:00
Day 9
Oct 10
Acajutla, El Salvador
arr 07:00 · dep 17:00
Day 10
Oct 11
At Sea
Day 11
Oct 12
At Sea
Day 13
Oct 14
Cartagena, Colombia
arr 12:00 · dep 18:00

Cartagena de Indias is a Caribbean port city of about 1 million people on Colombia's northern coast, and one of the best-preserved colonial cities in the Americas. The walled old city (Ciudad Amurallada) is a UNESCO World Heritage Site, built by the Spanish starting in the 16th century to protect the gold and silver being shipped back to Europe.

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Day 14
Oct 15
At Sea
Day 15
Oct 16
At Sea
Day 16
Oct 17
Half Moon Cay, Bahamas
arr 08:00 · dep 14:00

Half Moon Cay (officially renamed RelaxAway, Half Moon Cay in 2024) is Holland America Line's private Bahamian destination, also used by certain Carnival Cruise Line itineraries. The island sits in the southeast Bahamas, about 100 miles southeast of Nassau, in the Exuma chain.

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Day 17
Oct 18
Disembark
Fort Lauderdale (Port Everglades), Florida
arr 07:00

Fort Lauderdale cruise port, officially Port Everglades, is one of the busiest cruise ports in the world and the closest major competitor to PortMiami, just 25 miles to the south. It sits on the southeastern coast of Florida across the cities of Fort Lauderdale, Hollywood, and Dania Beach.

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1Embark/Debark3Port of CallRoute
Distance
≈ 3,935nm
At sea
7 of 16 nights
Type
One-way
Price history

Interior cabin

$2,309▲ $590 (34.3%) vs Mar 9
Low
$1,499
High
$2,489
Average
$1,936
Vs avg
+19%
$1,400$1,697$1,994$2,291$2,588Mar 9Jun 11Sep 13$1,719 · Mar 9$1,729 · Mar 21$1,629 · Mar 28$1,529 · May 2$1,949 · Jun 4$1,499 · Jun 10$1,949 · Jun 18$1,799 · Jun 24$2,199 · Jul 2$1,799 · Jul 8$2,199 · Jul 16$2,339 · Jul 18$1,899 · Jul 22$2,489 · Jul 30$2,309 · Aug 2$1,899 · Aug 12$1,799 · Aug 20$1,749 · Aug 23$2,309 · Sep 13

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This sailing appears to be sold out. Prices below are the last we saw.
Starting from
$2,309/person
Incl. taxes & port fees
Checked 15 days ago · Sep 13
Last change Sep 13: $1,749 → $2,309 (+$560)
Interior
$144/night
$2,309
Ocean View
$154/night
$2,459
Balcony
$165/night
$2,639
Spa
Last seen Aug 31
$3,389
Suite
Last seen Aug 28
$9,679

Track prices

Get emailed when double occupancy drops below your target.

Nieuw Amsterdam
Your ship
Nieuw Amsterdam
Holland America Line · Signature class · Built 2010
Passengers
2,106
Tonnage
86,273
Length
285m
Crew
929
Onboard
PoolHot TubCasinoTheaterPiano BarSports BarWine BarNight ClubBasketball CourtJogging TrackPickleballKids Club
Full ship profile →
Book from $2,309Instant checkout

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