Oosterdam: 21-Night Mediterranean - Western
This 21-night Mediterranean cruise aboard the Oosterdam by Holland America Line sails from Athens (Piraeus) to Barcelona, departing October 14, 2026, calling at Mykonos, Istanbul, Ephesus (Kusadasi), and 11 more ports, and returns November 4, 2026.
Athens cruise port is in Piraeus, a busy port city about 10 kilometers southwest of central Athens. Piraeus is its own city, not just a terminal, and it handles cruise ships, island ferries, and commercial traffic all at once.
Read more →Mykonos cruise port is one of the most instantly recognizable stops in the Greek islands. Whitewashed cube buildings cascade down hills to the Aegean Sea, blue-domed churches punctuate the skyline, and windmills stand sentinel on the ridge above Mykonos Town (Chora).
Read more →Istanbul cruise port is one of the most extraordinary arrivals in the world. Ships sail up the Bosphorus Strait between Europe and Asia, past Ottoman palaces and Byzantine ruins, and dock at Galataport, the underground cruise terminal in the Karaköy neighborhood right in the center of the city.
Read more →Istanbul cruise port is one of the most extraordinary arrivals in the world. Ships sail up the Bosphorus Strait between Europe and Asia, past Ottoman palaces and Byzantine ruins, and dock at Galataport, the underground cruise terminal in the Karaköy neighborhood right in the center of the city.
Read more →Kusadasi cruise port is Turkey's busiest and the primary gateway to Ephesus, one of the most significant ancient Greek and Roman cities in the world. The port sits on Turkey's central Aegean coast, about 95 kilometers south of Izmir, with ships docking at the Ege Ports cruise terminal right in the middle of town.
Read more →Rhodes is the largest of Greece's Dodecanese islands, sitting in the far southeastern Aegean Sea just 18 kilometers from the Turkish coast. The Rhodes cruise port is in the city of Rhodes on the island's northern tip, where ships dock right next to one of the best-preserved medieval old towns in Europe.
Read more →Athens cruise port is in Piraeus, a busy port city about 10 kilometers southwest of central Athens. Piraeus is its own city, not just a terminal, and it handles cruise ships, island ferries, and commercial traffic all at once.
Read more →Katakolon is a small fishing village on the western coast of the Peloponnese, with a permanent population of only about 700 people. It exists on cruise maps for one reason: ancient Olympia, the birthplace of the Olympic Games, is 45 minutes inland.
Read more →Valletta cruise port is one of the most visually dramatic arrivals on any Mediterranean itinerary. Ships sail into the Grand Harbour, a deep natural inlet flanked by honey-colored limestone walls that rise straight out of the water, with Valletta itself perched on the peninsula above.
Read more →Messina cruise port sits at the northeastern tip of Sicily, directly across the narrow Strait of Messina from mainland Italy. Ships dock right at the city waterfront, making it one of the easiest Mediterranean ports to step off and explore.
Read more →Naples cruise port is one of the most popular stops on Mediterranean itineraries, and it's easy to see why. The city sits on the Bay of Naples with Mount Vesuvius looming behind it, and it serves as the gateway to Pompeii, the Amalfi Coast, Capri, and Sorrento.
Read more →Rome's cruise port is in Civitavecchia, a working port town about 80 kilometers northwest of the city. That distance is the single most important thing to understand about this stop.
Read more →Nice is the capital of the French Riviera, a Mediterranean city of about 340,000 people wedged between the Maritime Alps and the Cote d'Azur coastline. Cruise ships anchor in the bay at Villefranche-sur-Mer, a small harbor town about 6 km east of Nice, or occasionally dock at Nice's own port.
Read more →Barcelona cruise port is the busiest in the Mediterranean, handling millions of passengers a year across multiple terminals. The city behind it earns that traffic.
Read more →Interior cabin
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Other Mediterranean departures
Questions about this sailing
Which ports does it visit?
It sails from Athens (Piraeus) to Barcelona and calls at Mykonos, Istanbul, Ephesus (Kusadasi), Kos, Rhodes Island, Athens (Piraeus), Katakolon, Saranda, Valletta, Messina, Naples, Rome (Civitavecchia), Ajaccio and Nice (Villefranche), with 5 days at sea.
