Oosterdam: 21-Night Mediterranean - Western

Oosterdam

This 21-night Mediterranean cruise aboard the Oosterdam by Holland America Line sails from Athens (Piraeus) to Barcelona, departing October 14, 2026, calling at Mykonos, Istanbul, Ephesus (Kusadasi), and 11 more ports, and returns November 4, 2026.

Days
21 nights
Departs
Oct 14, 2026
Ports
15
Returns
Nov 4, 2026
Sea days
5
Distance
2,502nm
Itinerary
Embark Port Sea
Day 1
Oct 14
Embark
Athens (Piraeus), Greece
dep 17:00

Athens cruise port is in Piraeus, a busy port city about 10 kilometers southwest of central Athens. Piraeus is its own city, not just a terminal, and it handles cruise ships, island ferries, and commercial traffic all at once.

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Day 2
Oct 15
Mykonos, Greece
arr 07:00 · dep 20:00

Mykonos cruise port is one of the most instantly recognizable stops in the Greek islands. Whitewashed cube buildings cascade down hills to the Aegean Sea, blue-domed churches punctuate the skyline, and windmills stand sentinel on the ridge above Mykonos Town (Chora).

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Day 3
Oct 16
At Sea
Day 4
Oct 17
Istanbul, Turkey
arr 07:00

Istanbul cruise port is one of the most extraordinary arrivals in the world. Ships sail up the Bosphorus Strait between Europe and Asia, past Ottoman palaces and Byzantine ruins, and dock at Galataport, the underground cruise terminal in the Karaköy neighborhood right in the center of the city.

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Day 5
Oct 18
Istanbul, Turkey
dep 23:00

Istanbul cruise port is one of the most extraordinary arrivals in the world. Ships sail up the Bosphorus Strait between Europe and Asia, past Ottoman palaces and Byzantine ruins, and dock at Galataport, the underground cruise terminal in the Karaköy neighborhood right in the center of the city.

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Day 6
Oct 19
At Sea
Day 7
Oct 20
Ephesus (Kusadasi), Turkey
arr 07:00 · dep 19:00

Kusadasi cruise port is Turkey's busiest and the primary gateway to Ephesus, one of the most significant ancient Greek and Roman cities in the world. The port sits on Turkey's central Aegean coast, about 95 kilometers south of Izmir, with ships docking at the Ege Ports cruise terminal right in the middle of town.

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Day 8
Oct 21
Kos, Greece
arr 08:00 · dep 18:00
Day 9
Oct 22
Rhodes Island, Greece
arr 08:00 · dep 21:00

Rhodes is the largest of Greece's Dodecanese islands, sitting in the far southeastern Aegean Sea just 18 kilometers from the Turkish coast. The Rhodes cruise port is in the city of Rhodes on the island's northern tip, where ships dock right next to one of the best-preserved medieval old towns in Europe.

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Day 10
Oct 23
At Sea
Day 11
Oct 24
Athens (Piraeus), Greece
arr 05:30 · dep 17:00

Athens cruise port is in Piraeus, a busy port city about 10 kilometers southwest of central Athens. Piraeus is its own city, not just a terminal, and it handles cruise ships, island ferries, and commercial traffic all at once.

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Day 12
Oct 25
Katakolon, Greece
arr 08:00 · dep 16:00

Katakolon is a small fishing village on the western coast of the Peloponnese, with a permanent population of only about 700 people. It exists on cruise maps for one reason: ancient Olympia, the birthplace of the Olympic Games, is 45 minutes inland.

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Day 13
Oct 26
Saranda, Albania
arr 10:00 · dep 18:00
Day 14
Oct 27
At Sea
Day 15
Oct 28
Valletta, Malta
arr 08:00 · dep 20:00

Valletta cruise port is one of the most visually dramatic arrivals on any Mediterranean itinerary. Ships sail into the Grand Harbour, a deep natural inlet flanked by honey-colored limestone walls that rise straight out of the water, with Valletta itself perched on the peninsula above.

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Day 16
Oct 29
Messina, Sicily, Italy
arr 08:00 · dep 17:00

Messina cruise port sits at the northeastern tip of Sicily, directly across the narrow Strait of Messina from mainland Italy. Ships dock right at the city waterfront, making it one of the easiest Mediterranean ports to step off and explore.

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Day 17
Oct 30
Naples, Italy
arr 07:00 · dep 18:00

Naples cruise port is one of the most popular stops on Mediterranean itineraries, and it's easy to see why. The city sits on the Bay of Naples with Mount Vesuvius looming behind it, and it serves as the gateway to Pompeii, the Amalfi Coast, Capri, and Sorrento.

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Day 18
Oct 31
Rome (Civitavecchia), Italy
arr 07:00 · dep 22:00

Rome's cruise port is in Civitavecchia, a working port town about 80 kilometers northwest of the city. That distance is the single most important thing to understand about this stop.

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Day 19
Nov 1
Ajaccio, France
arr 10:00 · dep 18:00
Day 20
Nov 2
Nice (Villefranche), France
arr 08:00 · dep 17:00

Nice is the capital of the French Riviera, a Mediterranean city of about 340,000 people wedged between the Maritime Alps and the Cote d'Azur coastline. Cruise ships anchor in the bay at Villefranche-sur-Mer, a small harbor town about 6 km east of Nice, or occasionally dock at Nice's own port.

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Day 21
Nov 3
At Sea
Day 22
Nov 4
Disembark
Barcelona, Spain
arr 07:00

Barcelona cruise port is the busiest in the Mediterranean, handling millions of passengers a year across multiple terminals. The city behind it earns that traffic.

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1Embark/Debark3Port of CallRoute
Distance
≈ 2,502nm
At sea
5 of 21 nights
Type
One-way
Price history

Interior cabin

$3,884last available Aug 14
Low
$3,734
High
$4,434
Average
$3,991
$3,664$3,874$4,084$4,294$4,504Mar 9May 27Aug 14$4,384 · Mar 9$4,434 · Mar 21$4,184 · Mar 29$4,084 · Apr 5$4,034 · May 9$4,094 · May 14$4,034 · May 17$3,884 · May 31$3,734 · Jun 19$3,794 · Jul 31$3,824 · Aug 5$3,794 · Aug 6$3,824 · Aug 8$3,884 · Aug 12$3,884 · Aug 14

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Questions

Questions about this sailing

Which ports does it visit?

It sails from Athens (Piraeus) to Barcelona and calls at Mykonos, Istanbul, Ephesus (Kusadasi), Kos, Rhodes Island, Athens (Piraeus), Katakolon, Saranda, Valletta, Messina, Naples, Rome (Civitavecchia), Ajaccio and Nice (Villefranche), with 5 days at sea.

This cruise has already sailed. Booking, saving, and price tracking are no longer available.
Last recorded from
$6,574/person
Incl. taxes & port fees
Interior
Last seen Aug 14
$3,884
Ocean View
Last seen Jul 29
$3,884
Balcony
$313/night
$6,574
Suite
$392/night
$8,234
Oosterdam
Your ship
Oosterdam
Holland America Line · Vista class · Built 2003
Passengers
1,964
Tonnage
82,820
Length
285m
Crew
812
Onboard
PoolHot TubCasinoTheaterPiano BarSports BarWine BarNight ClubJazz LoungeBasketball CourtJogging TrackPickleball
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