Regal Princess: 15-Night Mediterranean

London (Southampton) cruise port is the busiest cruise departure point in the United Kingdom and one of the largest in Northern Europe. The port sits in Southampton, a city on England's southern coast about 80 miles southwest of London.

Cadiz is the actual cruise port marketed as "Seville (Cadiz)" by cruise lines because Seville, Spain's fourth-largest city, is the primary day-trip draw from this port. Cadiz itself is one of Europe's oldest continuously inhabited cities, perched on a narrow peninsula jutting into the Atlantic on Spain's southwestern coast.

Barcelona cruise port is the busiest in the Mediterranean, handling millions of passengers a year across multiple terminals. The city behind it earns that traffic.

Florence (Livorno) cruise port is the main Tuscan stop on Mediterranean itineraries, but it's worth being clear about what you're actually docking at. The port is Livorno, a working industrial city on the Ligurian coast, about 85 kilometers west of Florence.

Ibiza is one of Spain's Balearic Islands in the western Mediterranean, about 150 km off the coast of Valencia. The cruise port is in Ibiza Town (Eivissa), on the southeast coast of the island.

Cartagena is a historic port city of about 215,000 people on Spain's southeastern Mediterranean coast, in the Murcia region. Founded by the Carthaginians in 227 BC (as Carthago Nova), the city has been contested by Carthaginians, Romans, Moors, and Spanish kingdoms, and its layered history shows in the archaeological sites scattered through the compact center.