Azamara Quest: 42-Night Grand Voyage

Miami cruise port, officially called PortMiami, is the busiest cruise port in the world by passenger volume. Millions of people pass through here every year, and nearly every major cruise line uses it as a home port.

Cozumel cruise port is one of the busiest in the Caribbean, with multiple ships docking on the island every day during peak season. Cozumel is a flat, laid-back island off the eastern coast of Mexico's Yucatán Peninsula, and it's been a cruise staple for decades.

Belize City is the largest city in Belize, a small Central American country on the Caribbean coast known for its barrier reef (the second largest in the world), jungle ruins, and laid-back culture. The city itself has about 60,000 residents and a rough, unpolished feel that can surprise passengers expecting a typical Caribbean port.

Roatan cruise port serves one of the Bay Islands of Honduras, a Caribbean destination famous for some of the best scuba diving in the Western Hemisphere. The island sits along the Mesoamerican Barrier Reef (the world's second-largest coral reef system) about 40 miles off the Honduras mainland.

Buenos Aires is Argentina's capital and the primary embarkation port for cruise itineraries to Patagonia, the Falkland Islands, Antarctica, and around South America. The cruise terminal (Terminal de Cruceros Benito Quinquela Martin) is in the Puerto Madero/La Boca area on the Rio de la Plata, about 3 km from the city center.