Oosterdam: 16-Night South America
This 16-night Panama Canal cruise aboard the Oosterdam by Holland America Line sails from Santiago (San Antonio) to Fort Lauderdale (Port Everglades), departing March 24, 2027, calling at Coquimbo, Lima (Callao), Trujillo (Salaverry), and 4 more ports, and returns April 9, 2027. Cabin prices start from $2,299 per person.
Grand Cayman is the largest of the three Cayman Islands, a British Overseas Territory in the western Caribbean known for Seven Mile Beach, exceptional diving, and its role as a major offshore financial center. George Town serves as the cruise port, but there's no pier large enough for cruise ships.
Read more →Fort Lauderdale cruise port, officially Port Everglades, is one of the busiest cruise ports in the world and the closest major competitor to PortMiami, just 25 miles to the south. It sits on the southeastern coast of Florida across the cities of Fort Lauderdale, Hollywood, and Dania Beach.
Read more →Interior cabin
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Questions about this sailing
How much does this cruise cost per night?
Interior cabins start at $2,299 per person for the 16 nights, about $144 a night, with taxes and port fees included. A balcony starts at $3,999, about $250 a night.
Is $2,299 a good price for this sailing?
It is the lowest interior price we have recorded for this sailing since March 9, 2026.
Which ports does it visit?
It sails from Santiago (San Antonio) to Fort Lauderdale (Port Everglades) and calls at Coquimbo, Lima (Callao), Trujillo (Salaverry), Manta, Panama City (Fuerte Amador), Panama Canal and Grand Cayman (George Town), with 6 days at sea.
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