21 Night Panama Canal Cruise
This 21-night Panama Canal cruise aboard the Nieuw Amsterdam by Holland America Line departs Fort Lauderdale (Port Everglades) on January 17, 2027, calling at Half Moon Cay, Port of Oranjestad, Cartagena, and 9 more ports, and returns February 7, 2027. Cabin prices start from $2,699 per person.
Fort Lauderdale cruise port, officially Port Everglades, is one of the busiest cruise ports in the world and the closest major competitor to PortMiami, just 25 miles to the south. It sits on the southeastern coast of Florida across the cities of Fort Lauderdale, Hollywood, and Dania Beach.
Read more →Half Moon Cay (officially renamed RelaxAway, Half Moon Cay in 2024) is Holland America Line's private Bahamian destination, also used by certain Carnival Cruise Line itineraries. The island sits in the southeast Bahamas, about 100 miles southeast of Nassau, in the Exuma chain.
Read more →Aruba's capital sits just 15 miles off the Venezuelan coast, and it's one of the southern Caribbean's most popular cruise stops for good reason. Five berths across three air-conditioned terminals handle up to five ships at once, with water depths of 32 to 36 feet.
Read more →Cartagena de Indias is a Caribbean port city of about 1 million people on Colombia's northern coast, and one of the best-preserved colonial cities in the Americas. The walled old city (Ciudad Amurallada) is a UNESCO World Heritage Site, built by the Spanish starting in the 16th century to protect the gold and silver being shipped back to Europe.
Read more →Grand Cayman is the largest of the three Cayman Islands, a British Overseas Territory in the western Caribbean known for Seven Mile Beach, exceptional diving, and its role as a major offshore financial center. George Town serves as the cruise port, but there's no pier large enough for cruise ships.
Read more →Fort Lauderdale cruise port, officially Port Everglades, is one of the busiest cruise ports in the world and the closest major competitor to PortMiami, just 25 miles to the south. It sits on the southeastern coast of Florida across the cities of Fort Lauderdale, Hollywood, and Dania Beach.
Read more →St. John's is the capital and main cruise port of Antigua, one of the Leeward Islands in the eastern Caribbean. The Heritage Quay and Redcliffe Quay cruise terminals sit in the heart of St. John's, directly adjacent to the duty-free shopping district.
Read more →St. Thomas cruise port is one of the busiest stops on Eastern Caribbean itineraries and the hub of the US Virgin Islands cruise scene. The port handles two main cruise terminals.
Read more →Tortola is the largest of the British Virgin Islands, a mountainous, lush Caribbean island where Road Town serves as the capital of this British Overseas Territory. The cruise port at Road Town Pier Park handles two large ships simultaneously (up to 180,000 GT).
Read more →San Juan cruise port is one of the busiest in the Caribbean and one of the few that doubles as both a major embarkation point and a popular port of call. The port sits in Old San Juan, the historic colonial core of Puerto Rico's capital, founded by Spanish colonists in 1521.
Read more →Half Moon Cay (officially renamed RelaxAway, Half Moon Cay in 2024) is Holland America Line's private Bahamian destination, also used by certain Carnival Cruise Line itineraries. The island sits in the southeast Bahamas, about 100 miles southeast of Nassau, in the Exuma chain.
Read more →Interior cabin
New to these charts? How to read cruise price history
Other Panama Canal departures
We may earn a commission when you book through this link, at no extra cost to you.
Track prices
Get emailed when double occupancy drops below your target.
We may earn a commission when you book through this link, at no extra cost to you.
