Oceania Sirena: 65-Night World
This 65-night Panama Canal cruise aboard the Oceania Sirena by Oceania Cruises departs Miami on January 5, 2028, calling at Grand Cayman (George Town), Ocho Rios, Santa Marta, and 28 more ports, and returns March 10, 2028. Cabin prices start from $24,949 per person.
Miami cruise port, officially called PortMiami, is the busiest cruise port in the world by passenger volume. Millions of people pass through here every year, and nearly every major cruise line uses it as a home port.
Read more →Grand Cayman is the largest of the three Cayman Islands, a British Overseas Territory in the western Caribbean known for Seven Mile Beach, exceptional diving, and its role as a major offshore financial center. George Town serves as the cruise port, but there's no pier large enough for cruise ships.
Read more →Cartagena de Indias is a Caribbean port city of about 1 million people on Colombia's northern coast, and one of the best-preserved colonial cities in the Americas. The walled old city (Ciudad Amurallada) is a UNESCO World Heritage Site, built by the Spanish starting in the 16th century to protect the gold and silver being shipped back to Europe.
Read more →Colon sits at the Atlantic (Caribbean) entrance to the Panama Canal, serving as the port of call for ships that transit the canal or stop before or after the crossing. The Colon 2000 cruise terminal and the nearby Cristobal pier handle the cruise traffic, both located away from the city center in secure port compounds.
Read more →Buenos Aires is Argentina's capital and the primary embarkation port for cruise itineraries to Patagonia, the Falkland Islands, Antarctica, and around South America. The cruise terminal (Terminal de Cruceros Benito Quinquela Martin) is in the Puerto Madero/La Boca area on the Rio de la Plata, about 3 km from the city center.
Read more →Rio de Janeiro is one of the most visually dramatic cities on earth, set between granite peaks, tropical forest, and Atlantic beaches. The city of about 6.
Read more →Barbados cruise port is in Bridgetown, the capital of the easternmost Caribbean island. Bridgetown Port (Deep Water Harbour) sits just outside the city's UNESCO-listed historic center, with modern terminal facilities including 21 duty-free shops, restaurants, car rental agencies, and a tourism office.
Read more →Pointe-a-Pitre is the economic capital of Guadeloupe, a French overseas department in the Lesser Antilles that gives you Caribbean beaches with French culture, cuisine, and infrastructure. The archipelago consists of two main islands shaped like a butterfly: Grande-Terre (flat, with beaches and sugar cane) and Basse-Terre (mountainous, with rainforest and a live volcano).
Read more →Tortola is the largest of the British Virgin Islands, a mountainous, lush Caribbean island where Road Town serves as the capital of this British Overseas Territory. The cruise port at Road Town Pier Park handles two large ships simultaneously (up to 180,000 GT).
Read more →Interior cabin
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Questions about this sailing
How much does this cruise cost per night?
Interior cabins start at $24,949 per person for the 65 nights, about $384 a night, with taxes and port fees included. A balcony starts at $34,599, about $532 a night.
Is $24,949 a good price for this sailing?
It is $4,400 above the lowest interior price we have recorded for this sailing since March 9, 2026 ($20,549 on March 9, 2026).
Which ports does it visit?
It sails round trip from Miami and calls at Grand Cayman (George Town), Ocho Rios, Santa Marta, Cartagena, Colon, Panama Canal, Manta, Trujillo (Salaverry), Lima (Callao), Pisco, Arica, Antofagasta, Valparaiso, Puerto Montt, Chiloe Island, Puerto Chacabuco, Punta Arenas, Ushuaia (Tierra del Fuego), Port Stanley, Puerto Madryn, Buenos Aires, Punta del Este, Rio de Janeiro, Maceio, Santarem, Boca da Valeria, Manaus, Parintins, Barbados, Pointe-a-Pitre and Tortola, with 32 days at sea.
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