Queen Anne: 27-Night World

London (Southampton) cruise port is the busiest cruise departure point in the United Kingdom and one of the largest in Northern Europe. The port sits in Southampton, a city on England's southern coast about 80 miles southwest of London.

Orlando's cruise port is Port Canaveral, located on Florida's Space Coast about 45 miles east of the city. It's one of the busiest cruise ports in the world, and almost entirely an embarkation port.

Miami cruise port, officially called PortMiami, is the busiest cruise port in the world by passenger volume. Millions of people pass through here every year, and nearly every major cruise line uses it as a home port.

Cartagena de Indias is a Caribbean port city of about 1 million people on Colombia's northern coast, and one of the best-preserved colonial cities in the Americas. The walled old city (Ciudad Amurallada) is a UNESCO World Heritage Site, built by the Spanish starting in the 16th century to protect the gold and silver being shipped back to Europe.

Los Angeles cruise port is in San Pedro, a harbor neighborhood at the southern tip of the city, about 25 miles from downtown LA and 18 miles from LAX. The port is called the World Cruise Center, and it's the main departure point for Mexican Riviera, Hawaii, and Pacific Coast itineraries.