Brilliant Lady: 17-Night Panama Canal from Los Angeles
This 17-night Mexico & Central America cruise aboard the Brilliant Lady by Virgin Voyages sails from Los Angeles to Miami, departing October 29, 2026, calling at Cabo San Lucas, Puerto Quetzal, Puerto Caldera, Cartagena, and returns November 15, 2026.
Los Angeles cruise port is in San Pedro, a harbor neighborhood at the southern tip of the city, about 25 miles from downtown LA and 18 miles from LAX. The port is called the World Cruise Center, and it's the main departure point for Mexican Riviera, Hawaii, and Pacific Coast itineraries.
Read more →Cabo San Lucas sits at the very tip of Mexico's Baja California Peninsula, where the Pacific Ocean meets the Sea of Cortez. This is a tender port: ships anchor in Cabo San Lucas Bay and passengers ride small boats to the marina.
Read more →Cartagena de Indias is a Caribbean port city of about 1 million people on Colombia's northern coast, and one of the best-preserved colonial cities in the Americas. The walled old city (Ciudad Amurallada) is a UNESCO World Heritage Site, built by the Spanish starting in the 16th century to protect the gold and silver being shipped back to Europe.
Read more →Cartagena de Indias is a Caribbean port city of about 1 million people on Colombia's northern coast, and one of the best-preserved colonial cities in the Americas. The walled old city (Ciudad Amurallada) is a UNESCO World Heritage Site, built by the Spanish starting in the 16th century to protect the gold and silver being shipped back to Europe.
Read more →Miami cruise port, officially called PortMiami, is the busiest cruise port in the world by passenger volume. Millions of people pass through here every year, and nearly every major cruise line uses it as a home port.
Read more →Interior cabin
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Other Mexico & Central America departures
Questions about this sailing
Which ports does it visit?
It sails from Los Angeles to Miami and calls at Cabo San Lucas, Puerto Quetzal, Puerto Caldera and Cartagena, with 11 days at sea.