18 Night Grand Voyage Cruise

MSC Opera

This 18-night Mediterranean (Western) cruise aboard the MSC Opera by MSC Cruises sails from Rome (Civitavecchia) to La Romana, departing October 29, 2026, calling at Genoa, Florence (Livorno), Marseille, and 5 more ports, and returns November 16, 2026. Cabin prices start from $670 per person.

Days
18 nights
Departs
Oct 29, 2026
Ports
10
Returns
Nov 16, 2026
Sea days
9
Distance
4,833nm
Itinerary
Embark Port Sea
Day 1
Oct 29
Embark
Rome (Civitavecchia), Italy
dep 19:00

Rome's cruise port is in Civitavecchia, a working port town about 80 kilometers northwest of the city. That distance is the single most important thing to understand about this stop.

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Day 2
Oct 30
Genoa, Italy
arr 08:00 · dep 18:00

Genoa cruise port is one of the main embarkation points for western Mediterranean itineraries, particularly for MSC and Costa Cruises, which both have roots here. The city is the capital of Liguria and the birthplace of Christopher Columbus, pesto, and focaccia, and it has a grittier, more working-class feel than the polished Italian cities most tourists flock to.

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Day 3
Oct 31
Florence (Livorno), Italy
arr 08:00 · dep 18:00

Florence (Livorno) cruise port is the main Tuscan stop on Mediterranean itineraries, but it's worth being clear about what you're actually docking at. The port is Livorno, a working industrial city on the Ligurian coast, about 85 kilometers west of Florence.

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Day 4
Nov 1
Marseille, France
arr 09:00 · dep 18:00

Marseille cruise port is France's busiest and one of the major stops on western Mediterranean itineraries. The city is France's second largest and its oldest, founded by Greek sailors over 2,600 years ago, and it has a rougher, more authentic edge than the polished Riviera towns further east.

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Day 5
Nov 2
Barcelona, Spain
arr 07:00 · dep 16:00

Barcelona cruise port is the busiest in the Mediterranean, handling millions of passengers a year across multiple terminals. The city behind it earns that traffic.

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Day 6
Nov 3
At Sea
Day 7
Nov 4
Tangier, Morocco
arr 08:00 · dep 17:00

Tangier sits at the northwestern tip of Africa, where the Mediterranean meets the Atlantic and Morocco looks across the Strait of Gibraltar at Spain, just 14 km away. The city has about 1.

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Day 8
Nov 5
At Sea
Day 9
Nov 6
At Sea
Day 10
Nov 7
At Sea
Day 11
Nov 8
At Sea
Day 12
Nov 9
At Sea
Day 13
Nov 10
At Sea
Day 14
Nov 11
At Sea
Day 15
Nov 12
Antigua (St. John's)
arr 09:00 · dep 18:00

St. John's is the capital and main cruise port of Antigua, one of the Leeward Islands in the eastern Caribbean. The Heritage Quay and Redcliffe Quay cruise terminals sit in the heart of St. John's, directly adjacent to the duty-free shopping district.

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Day 16
Nov 13
St. Maarten (Philipsburg)
arr 09:00 · dep 18:00

St. Maarten cruise port is one of the busiest in the Caribbean, with ships docking at the A.C.

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Day 17
Nov 14
Basseterre St Kitts, Port Zante
arr 08:00 · dep 18:00

Basseterre cruise port in St. Kitts uses the Port Zante terminal, a purpose-built cruise facility in the heart of Basseterre, the capital of St. Kitts and Nevis. Port Zante includes two dedicated cruise piers capable of berthing the largest modern ships plus a marina, restaurants, shops, and the Amina Craft Market.

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Day 18
Nov 15
At Sea
Day 19
Nov 16
Disembark
La Romana, Dominican Republic
arr 07:00

Most cruise passengers arriving at La Romana are headed somewhere else - Casa de Campo, the Caribbean's most exclusive resort complex, or Altos de Chavon, a replica Mediterranean village perched on a cliff above the Chavon River. Cruise ships dock at the Central Romana port, about a 10-minute drive from the Casa de Campo resort area.

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Loading map...
1Embark/Debark3Port of CallRoute
Distance
≈ 4,833nm
At sea
9 of 18 nights
Type
One-way
Price history

Interior cabin

$670▼ $347 (34.1%) vs Mar 9
Low
$670
High
$1,077
Average
$863
Vs avg
−22%
$629$751$874$996$1,118Mar 9Jun 18Sep 28$1,017 · Mar 9$916 · Apr 23$673 · Jun 20$948 · Jul 9$1,077 · Jul 20$935 · Jul 30$670 · Sep 9$670 · Sep 28

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Starting from
$670/person
Incl. taxes & port fees
Checked today · Sep 28
Last change Sep 9: $935 → $670 (−$265)
Interior
$37/night
$670
Ocean View
$45/night
$802
Balcony
Last seen Sep 23
$1,905
Spa
Last seen Sep 23
$3,105
Suite
$215/night
$3,870

Track prices

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MSC Opera
Your ship
MSC Opera
MSC Cruises · Lirica class · Built 2004
Passengers
2,150
Tonnage
65,591
Length
275m
Crew
728
Onboard
PoolHot TubWater ParkSpaSaunaSteam RoomThermal SuiteHair SalonFitness CenterJogging TrackMini GolfVideo Arcade
Full ship profile →
Book from $670Instant checkout

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