Costa Pacifica: 12-Night Mediterranean from Savona (Genoa)

Savona cruise port is the main homeport for Costa Crociere (Costa Cruises), Italy's largest cruise line. Savona sits on the Italian Riviera (Liguria region) about 45 kilometers southwest of Genoa and 170 kilometers north of Nice.

Rome's cruise port is in Civitavecchia, a working port town about 80 kilometers northwest of the city. That distance is the single most important thing to understand about this stop.

Messina cruise port sits at the northeastern tip of Sicily, directly across the narrow Strait of Messina from mainland Italy. Ships dock right at the city waterfront, making it one of the easiest Mediterranean ports to step off and explore.

Athens cruise port is in Piraeus, a busy port city about 10 kilometers southwest of central Athens. Piraeus is its own city, not just a terminal, and it handles cruise ships, island ferries, and commercial traffic all at once.

Istanbul cruise port is one of the most extraordinary arrivals in the world. Ships sail up the Bosphorus Strait between Europe and Asia, past Ottoman palaces and Byzantine ruins, and dock at Galataport, the underground cruise terminal in the Karaköy neighborhood right in the center of the city.

Santorini cruise port is one of the most visually striking arrivals in cruising. Ships anchor in the flooded caldera of a volcanic crater, with the whitewashed villages of Fira and Oia perched dramatically 1,000 feet above on the cliff edge.