Oceania Sonata: 13-Night Mediterranean from Rome (Civitavecchia)

Rome's cruise port is in Civitavecchia, a working port town about 80 kilometers northwest of the city. That distance is the single most important thing to understand about this stop.

Salerno is the eastern gateway to the Amalfi Coast, one of Italy's most celebrated stretches of coastline. Cruise ships dock at the Stazione Marittima in Salerno's port, a short walk from the city center and the starting point for trips along the legendary coastal road to Amalfi, Positano, and Ravello.

Messina cruise port sits at the northeastern tip of Sicily, directly across the narrow Strait of Messina from mainland Italy. Ships dock right at the city waterfront, making it one of the easiest Mediterranean ports to step off and explore.

Valletta cruise port is one of the most visually dramatic arrivals on any Mediterranean itinerary. Ships sail into the Grand Harbour, a deep natural inlet flanked by honey-colored limestone walls that rise straight out of the water, with Valletta itself perched on the peninsula above.

La Goulette is the cruise port serving Tunis, Tunisia's capital, located on the Mediterranean coast of North Africa about 12 kilometers northeast of the city center. The port sits at the entrance to the Lake of Tunis, a shallow lagoon separating La Goulette from downtown.

Cagliari is the capital of Sardinia, Italy's second-largest island, on the island's southern coast. The cruise port (Porto di Cagliari) sits directly at the edge of the old town, about a 10-minute walk from Piazza Matteotti and the base of the historic Castello district.

Alicante is a mid-sized Spanish city of about 330,000 people on the Costa Blanca in southeastern Spain. It's a working Mediterranean city that happens to have a beautiful waterfront, a hilltop castle, and some of the best weather in Europe.

Cartagena is a historic port city of about 215,000 people on Spain's southeastern Mediterranean coast, in the Murcia region. Founded by the Carthaginians in 227 BC (as Carthago Nova), the city has been contested by Carthaginians, Romans, Moors, and Spanish kingdoms, and its layered history shows in the archaeological sites scattered through the compact center.

Malaga cruise port is the main gateway to Spain's Costa del Sol and Andalusia. The city sits on Spain's southern coast, about 130 kilometers west of Granada and 50 kilometers east of Marbella.

Cadiz is the actual cruise port marketed as "Seville (Cadiz)" by cruise lines because Seville, Spain's fourth-largest city, is the primary day-trip draw from this port. Cadiz itself is one of Europe's oldest continuously inhabited cities, perched on a narrow peninsula jutting into the Atlantic on Spain's southwestern coast.