22-Night Mediterranean from Athens (Piraeus)

Athens cruise port is in Piraeus, a busy port city about 10 kilometers southwest of central Athens. Piraeus is its own city, not just a terminal, and it handles cruise ships, island ferries, and commercial traffic all at once.

Istanbul cruise port is one of the most extraordinary arrivals in the world. Ships sail up the Bosphorus Strait between Europe and Asia, past Ottoman palaces and Byzantine ruins, and dock at Galataport, the underground cruise terminal in the Karaköy neighborhood right in the center of the city.

Istanbul cruise port is one of the most extraordinary arrivals in the world. Ships sail up the Bosphorus Strait between Europe and Asia, past Ottoman palaces and Byzantine ruins, and dock at Galataport, the underground cruise terminal in the Karaköy neighborhood right in the center of the city.

Santorini cruise port is one of the most visually striking arrivals in cruising. Ships anchor in the flooded caldera of a volcanic crater, with the whitewashed villages of Fira and Oia perched dramatically 1,000 feet above on the cliff edge.

Rome's cruise port is in Civitavecchia, a working port town about 80 kilometers northwest of the city. That distance is the single most important thing to understand about this stop.

Monaco is a sovereign city-state on the French Riviera, just 2 square kilometers in size with about 39,000 residents, making it the second-smallest country in the world. Monte Carlo, its most famous district, is synonymous with wealth, casinos, and Formula 1 racing.

Built on a narrow strip of land between the Mediterranean and the Etang de Thau lagoon, Sete is a working fishing port of about 45,000 people on the Languedoc coast. The city calls itself the Venice of Languedoc for its network of canals, though the comparison undersells what makes Sete different: this is a genuine fishing town where trawlers unload the catch at the port each morning and the restaurants cook what came in that day.

Barcelona cruise port is the busiest in the Mediterranean, handling millions of passengers a year across multiple terminals. The city behind it earns that traffic.

Palma de Mallorca cruise port is one of the busiest in the Mediterranean and the main cruise gateway to the Balearic Islands. Palma sits on the south coast of Mallorca, the largest of the Balearics, about 250 kilometers south of Barcelona.

Alicante is a mid-sized Spanish city of about 330,000 people on the Costa Blanca in southeastern Spain. It's a working Mediterranean city that happens to have a beautiful waterfront, a hilltop castle, and some of the best weather in Europe.

Cartagena is a historic port city of about 215,000 people on Spain's southeastern Mediterranean coast, in the Murcia region. Founded by the Carthaginians in 227 BC (as Carthago Nova), the city has been contested by Carthaginians, Romans, Moors, and Spanish kingdoms, and its layered history shows in the archaeological sites scattered through the compact center.

Malaga cruise port is the main gateway to Spain's Costa del Sol and Andalusia. The city sits on Spain's southern coast, about 130 kilometers west of Granada and 50 kilometers east of Marbella.

Gibraltar is a British Overseas Territory at the southern tip of the Iberian Peninsula, a 6.7-square-kilometer enclave dominated by the Rock of Gibraltar, a 426-meter limestone monolith that guards the western entrance to the Mediterranean.

Tangier sits at the northwestern tip of Africa, where the Mediterranean meets the Atlantic and Morocco looks across the Strait of Gibraltar at Spain, just 14 km away. The city has about 1.

Cadiz is the actual cruise port marketed as "Seville (Cadiz)" by cruise lines because Seville, Spain's fourth-largest city, is the primary day-trip draw from this port. Cadiz itself is one of Europe's oldest continuously inhabited cities, perched on a narrow peninsula jutting into the Atlantic on Spain's southwestern coast.

Cadiz is the actual cruise port marketed as "Seville (Cadiz)" by cruise lines because Seville, Spain's fourth-largest city, is the primary day-trip draw from this port. Cadiz itself is one of Europe's oldest continuously inhabited cities, perched on a narrow peninsula jutting into the Atlantic on Spain's southwestern coast.