MSC Opera: 16-Night Grand Voyage
This 16-night Caribbean (Eastern) cruise aboard the MSC Opera by MSC Cruises sails from Florence (Livorno) to La Romana, departing October 31, 2026, calling at Marseille, Barcelona, Tangier, and 3 more ports, and returns November 16, 2026.
Florence (Livorno) cruise port is the main Tuscan stop on Mediterranean itineraries, but it's worth being clear about what you're actually docking at. The port is Livorno, a working industrial city on the Ligurian coast, about 85 kilometers west of Florence.
Read more →Marseille cruise port is France's busiest and one of the major stops on western Mediterranean itineraries. The city is France's second largest and its oldest, founded by Greek sailors over 2,600 years ago, and it has a rougher, more authentic edge than the polished Riviera towns further east.
Read more →Barcelona cruise port is the busiest in the Mediterranean, handling millions of passengers a year across multiple terminals. The city behind it earns that traffic.
Read more →Tangier sits at the northwestern tip of Africa, where the Mediterranean meets the Atlantic and Morocco looks across the Strait of Gibraltar at Spain, just 14 km away. The city has about 1.
Read more →St. John's is the capital and main cruise port of Antigua, one of the Leeward Islands in the eastern Caribbean. The Heritage Quay and Redcliffe Quay cruise terminals sit in the heart of St. John's, directly adjacent to the duty-free shopping district.
Read more →St. Maarten cruise port is one of the busiest in the Caribbean, with ships docking at the A.C.
Read more →Basseterre cruise port in St. Kitts uses the Port Zante terminal, a purpose-built cruise facility in the heart of Basseterre, the capital of St. Kitts and Nevis. Port Zante includes two dedicated cruise piers capable of berthing the largest modern ships plus a marina, restaurants, shops, and the Amina Craft Market.
Read more →Most cruise passengers arriving at La Romana are headed somewhere else - Casa de Campo, the Caribbean's most exclusive resort complex, or Altos de Chavon, a replica Mediterranean village perched on a cliff above the Chavon River. Cruise ships dock at the Central Romana port, about a 10-minute drive from the Casa de Campo resort area.
Read more →Interior cabin
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Other Caribbean (Eastern) departures
Questions about this sailing
Which ports does it visit?
It sails from Florence (Livorno) to La Romana and calls at Marseille, Barcelona, Tangier, Antigua (St. John's), St. Maarten (Philipsburg) and St. Kitts, with 9 days at sea.