Nieuw Amsterdam: 21-Night South America
This 21-night South America cruise aboard the Nieuw Amsterdam by Holland America Line sails from San Diego to Santiago (San Antonio), departing October 12, 2027, calling at Cabo San Lucas, Huatulco, Puerto Quetzal, and 7 more ports, and returns November 2, 2027. Cabin prices start from $2,954 per person.
San Diego is a major cruise port on the Southern California coast, about 120 miles south of Los Angeles and directly on the Mexican border. The B Street Cruise Ship Terminal and adjacent Broadway Pier sit in downtown San Diego along the Embarcadero waterfront, within walking distance of the Gaslamp Quarter, Seaport Village, and the USS Midway Museum.
Read more →Cabo San Lucas sits at the very tip of Mexico's Baja California Peninsula, where the Pacific Ocean meets the Sea of Cortez. This is a tender port: ships anchor in Cabo San Lucas Bay and passengers ride small boats to the marina.
Read more →Interior cabin
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Questions about this sailing
How much does this cruise cost per night?
Interior cabins start at $2,954 per person for the 21 nights, about $141 a night, with taxes and port fees included. A balcony starts at $4,314, about $205 a night.
Is $2,954 a good price for this sailing?
It is $170 above the lowest interior price we have recorded for this sailing since March 9, 2026 ($2,784 on June 20, 2026).
Which ports does it visit?
It sails from San Diego to Santiago (San Antonio) and calls at Cabo San Lucas, Huatulco, Puerto Quetzal, Puerto Caldera, Manta, Trujillo (Salaverry), Lima (Callao), Pisco, Arica and La Serena (Coquimbo), with 8 days at sea.
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