Crystal Serenity: 28-Night Fort Lauderdale To San Diego
This 28-night Panama Canal cruise aboard the Crystal Serenity by Crystal Cruises sails from Fort Lauderdale (Port Everglades) to San Diego, departing November 23, 2026, calling at Nassau, Samana, San Juan, and 14 more ports, and returns December 21, 2026. Cabin prices start from $17,000 per person.
Fort Lauderdale cruise port, officially Port Everglades, is one of the busiest cruise ports in the world and the closest major competitor to PortMiami, just 25 miles to the south. It sits on the southeastern coast of Florida across the cities of Fort Lauderdale, Hollywood, and Dania Beach.
Read more →Nassau cruise port is one of the most visited in the Caribbean, with up to six ships docking at Prince George Wharf on a busy day. The port sits directly on Bay Street in downtown Nassau, so you're essentially stepping off the ship and into the city.
Read more →San Juan cruise port is one of the busiest in the Caribbean and one of the few that doubles as both a major embarkation point and a popular port of call. The port sits in Old San Juan, the historic colonial core of Puerto Rico's capital, founded by Spanish colonists in 1521.
Read more →Known as 'One Happy Island,' Aruba docks ships at the port in Oranjestad, just steps from the colorful Dutch colonial architecture and Royal Plaza Mall. Eagle Beach and Palm Beach offer powdery white sand, and the island sits outside the hurricane belt.
Read more →Cartagena de Indias is a Caribbean port city of about 1 million people on Colombia's northern coast, and one of the best-preserved colonial cities in the Americas. The walled old city (Ciudad Amurallada) is a UNESCO World Heritage Site, built by the Spanish starting in the 16th century to protect the gold and silver being shipped back to Europe.
Read more →Cartagena de Indias is a Caribbean port city of about 1 million people on Colombia's northern coast, and one of the best-preserved colonial cities in the Americas. The walled old city (Ciudad Amurallada) is a UNESCO World Heritage Site, built by the Spanish starting in the 16th century to protect the gold and silver being shipped back to Europe.
Read more →You've probably seen photos of Willemstad even if you don't realize it: that row of pastel-colored Dutch colonial buildings along the Handelskade is one of the most photographed waterfronts in the Caribbean. It's been a UNESCO World Heritage Site since 1997.
Read more →A diver's and snorkeler's paradise, Bonaire is surrounded by a protected marine park with over 80 marked dive sites accessible from shore. The island's laid-back atmosphere and flamingo sanctuary at Goto Lake offer a quieter Caribbean experience.
Read more →Known as 'One Happy Island,' Aruba docks ships at the port in Oranjestad, just steps from the colorful Dutch colonial architecture and Royal Plaza Mall. Eagle Beach and Palm Beach offer powdery white sand, and the island sits outside the hurricane belt.
Read more →Stretched along Banderas Bay with the Sierra Madre mountains rising directly behind the shoreline, Puerto Vallarta draws about 290,000 residents year-round and far more during the winter cruise season. The city has managed to grow as a tourist destination while keeping its Mexican identity intact, particularly in the Zona Romantica and the malecon (boardwalk) areas where local life and tourism coexist on the same streets.
Read more →San Diego is a major cruise port on the Southern California coast, about 120 miles south of Los Angeles and directly on the Mexican border. The B Street Cruise Ship Terminal and adjacent Broadway Pier sit in downtown San Diego along the Embarcadero waterfront, within walking distance of the Gaslamp Quarter, Seaport Village, and the USS Midway Museum.
Read more →Balcony cabin
New to these charts? How to read cruise price history
Other Panama Canal departures
Questions about this sailing
How much does this cruise cost per night?
Ocean view cabins start at $17,000 per person for the 28 nights, about $607 a night, with taxes and port fees included. A balcony starts at $19,000, about $679 a night.
Is $17,000 a good price for this sailing?
It is $4,200 above the lowest ocean view price we have recorded for this sailing since March 9, 2026 ($12,800 on March 9, 2026).
Which ports does it visit?
It sails from Fort Lauderdale (Port Everglades) to San Diego and calls at Nassau, Samana, San Juan, Jost Van Dyke, Aruba, Cartagena, Curacao, Bonaire, Santa Marta, Panama Canal, Panama City (Fuerte Amador), Puerto Caldera, Playa Flamingo, Acajutla, Zihuatanejo, Manzanillo and Puerto Vallarta, with 8 days at sea.
We may earn a commission when you book through this link, at no extra cost to you.
Get a price-drop alert
Pick the cabins to watch. We check prices daily and email you when one drops. New accounts get a free 14-day Pro trial: every cabin, plus texts. No card.
We may earn a commission when you book through this link, at no extra cost to you.
