Nieuw Amsterdam: 26-Night South America
This 26-night South America cruise aboard the Nieuw Amsterdam by Holland America Line sails from Vancouver to Santiago (San Antonio), departing October 7, 2027, calling at San Francisco, San Diego, Cabo San Lucas, and 9 more ports, and returns November 2, 2027. Cabin prices start from $3,409 per person.
Vancouver cruise port is the main gateway to Alaska, and nearly every Alaska cruise that runs the full Inside Passage route starts or ends here. The terminal is at Canada Place, a distinctive sail-shaped building right on the downtown waterfront.
Read more →San Francisco is a compact city of about 870,000 people on the tip of a peninsula between the Pacific Ocean and San Francisco Bay, connected to the north by the Golden Gate Bridge and to the east by the Bay Bridge. The city's terrain is famously steep, its climate famously foggy, and its personality famously independent.
Read more →San Diego is a major cruise port on the Southern California coast, about 120 miles south of Los Angeles and directly on the Mexican border. The B Street Cruise Ship Terminal and adjacent Broadway Pier sit in downtown San Diego along the Embarcadero waterfront, within walking distance of the Gaslamp Quarter, Seaport Village, and the USS Midway Museum.
Read more →Cabo San Lucas sits at the very tip of Mexico's Baja California Peninsula, where the Pacific Ocean meets the Sea of Cortez. This is a tender port: ships anchor in Cabo San Lucas Bay and passengers ride small boats to the marina.
Read more →Interior cabin
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Other South America departures
Questions about this sailing
How much does this cruise cost per night?
Interior cabins start at $3,409 per person for the 26 nights, about $131 a night, with taxes and port fees included. A balcony starts at $5,009, about $193 a night.
Is $3,409 a good price for this sailing?
It is $100 above the lowest interior price we have recorded for this sailing since March 9, 2026 ($3,309 on April 12, 2026).
Which ports does it visit?
It sails from Vancouver to Santiago (San Antonio) and calls at San Francisco, San Diego, Cabo San Lucas, Huatulco, Puerto Quetzal, Puerto Caldera, Manta, Trujillo (Salaverry), Lima (Callao), Pisco, Arica and La Serena (Coquimbo), with 11 days at sea.
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